Early antibiotic treatment for chronic disorder shows improvement
May 26th, 2010 - 3:17 pm ICT by ANIWashington, May 26 (ANI): Medical experts have discovered that if patients suffering from chronic obstructive pulmonary disease (COPD) were treated with antibiotics at an early stage, they showed more improvement compared to those who received the treatment later, or not at all.
“Acute exacerbations of COPD are responsible for more than 600,000 hospitalizations annually, resulting in direct costs of more than 20 billion dollars,” the authors write.
“Guidelines recommend antibiotic therapy for acute exacerbations of COPD, but the evidence is based on small, heterogeneous trials, few of which include hospitalized patients.”
Michael B. Rothberg, M.D., M.P.H., of Baystate Medical Center, Springfield, Mass., and colleagues conducted a study at 413 acute care facilities throughout the United States, between January 2006 and December 2007, for patients suffering from acute exacerbations of COPD.
Of 84,621 patients, 79 percent received at least 2 consecutive days of antibiotic treatment. The factors studied were the initiation of mechanical ventilation after the second hospital day, inpatient mortality, or readmission for acute exacerbations of COPD within 30 days of discharge; length of stay, and hospital costs.
The researchers found that compared with patients not receiving antibiotics in the first 2 days, antibiotic-treated patients were less likely to receive mechanical ventilation after the second hospital day.
Also, patients treated with and without antibiotics had similar lengths of stay, but patients treated with antibiotics had lower costs.
The researchers add that two findings - all patient groups seemed to benefit from therapy and that harms were minimal, support the notion that all patients hospitalized with acute exacerbations of COPD should be prescribed antibiotics.
Identifying COPD patients, who do not have a bacterial etiology for their exacerbation, is difficult because sputum cultures do not distinguish between active infection and colonization.
“… until more data are available, routine use of antibiotics for acute exacerbations of COPD may be appropriate,” the authors conclude.
The study appears in the May 26 issue of JAMA. (ANI)
- Inhaled corticosteroid therapy helps reduce pneumonia mortality - Apr 16, 2011
- Controlled oxygen therapy slashes death rate among COPD patients - Oct 22, 2010
- Gene therapy may help treat lethal childhood muscle disorder - Mar 01, 2010
- Lung cancer mostly diagnosed late (Nov 17 is World Lung Cancer Day) - Nov 17, 2011
- Osteopathic treatment-conventional care combo cuts hospital stays for pneumonia patients - May 26, 2010
- Viral infection unlikely to advance deadly lung disease - Feb 27, 2011
- Prevent gum disease to keep lungs healthy - Jan 19, 2011
- Music 'eases' stress of assisted breathing - Dec 08, 2010
- Body chemical may help critically ill to improve - Aug 04, 2011
- Antibiotics Often Unnecessary for Kid's Ear Infections - Nov 18, 2010
- WHO calls for dealing with multi-drug resistant microbes - Apr 07, 2011
- Pneumonia kills more children than any other disease - Nov 02, 2009
- Baby Falak still critical (Lead) - Feb 06, 2012
- Protein shows promise in treating smoker's diseases - Jan 16, 2012
- Bacteria linked to asthma attacks in children - Oct 08, 2010
Tags: acute care facilities, acute exacerbations, antibiotic therapy, antibiotic treatment, bacterial etiology, baystate medical center, baystate medical center springfield, chronic disorder, chronic obstructive pulmonary disease, copd patients, exacerbation, mechanical ventilation, medical experts, minimal support, obstructive pulmonary disease, patient groups, readmission, rothberg, springfield mass, sputum cultures