Different genes behind smoking risk in adolescence and adulthoodApril 1st, 2011 - 4:45 pm ICT by ANI
Washington, April 1 (ANI): Scientists have found that different sets of genes are implicated in the risk for smoking addiction in adolescence and adulthood.
They found that teenagers carrying variants in two gene regions were three times more likely to become regular smokers in adolescence and twice as likely to be persistent smokers in adulthood, compared to non-carriers.
Variation in a set of dopamine-related genes was associated with a person’s risk of starting smoking, and these genes had a stronger impact on smoking initiation in adolescents than in adults.
Individuals carrying the risk variants had a 1.3-fold increased risk of starting smoking in their teenage years.
The other set of genes coded for subunits of the nicotinic cholinergic receptors, the brain targets for nicotine inhaled during smoking.
Variation in these genes influenced the likelihood of smokers continuing the habit into adulthood, as it had a stronger influence on the smoking habits of adults than of adolescents.
Those carrying these variants had a 1.3-fold increased risk of becoming a heavy and persistent smoker in adulthood.
The researchers said the findings could help develop genetic testing for those wishing to know their susceptibility to nicotine dependence and tobacco-related disease.
It could also pave the way for targeted drugs that influence an individual’s response to nicotine.
The findings appear in the April 1 issue of Biological Psychiatry. (ANI)
- Genes identified for childhood obesity - Apr 10, 2012
- Nicotine raises blood sugar among diabetic smokers: Study - Mar 28, 2011
- Tobacco smoking negatively affects teens' brains - Mar 03, 2011
- Asthma linked to smoking, nicotine dependence - Mar 31, 2011
- Scientists shed light on why some people cannot give up nicotine - Jan 31, 2011
- Struggling to quit smoking? blame your genes! - Apr 27, 2010
- Smoking may be in your genes - Apr 26, 2010
- Tobacco control is most cost-effective way to prevent cancer - Feb 04, 2010
- Want to quit smoking? Get professional help - Jan 04, 2011
- Smokers carrying common gene variants at greater aneurysm risk - Feb 27, 2010
- Tobacco major cause of cancer deaths: Study - Apr 02, 2012
- Cannabis smoking permanently lowers IQ - Aug 29, 2012
- Tobacco in candy form can lead to accidental poisoning in kids: Study - Apr 19, 2010
- Kids born to smoking mums 'more likely to become smokers' - Mar 22, 2011
- Say Yes To Life: Say No To Tobacco - May 27, 2010
Tags: , , , , , , , , , , , , , , , , , , ,