Cumulative lead exposure may impair women’s cognition in later yearsMarch 29th, 2009 - 3:00 pm ICT by ANI
Washington, March 29 (ANI): Cumulative exposure to lead at levels likely to be experienced in community settings may have adverse consequences for women’s cognition in their later years, according to a study.
The study, supported by the National Institute of Environmental Health Sciences, was conducted with a view to examine biomarkers of lead exposure in relation to performance on cognitive tests given to older women.
Lead exposure is measured in two ways-blood lead level, which is a reading of recent lead dosage; and bone lead level, which is a cumulative measure of lead exposure over many years.
The current study involved the assessment of bone lead levels in the tibia and the patella.
The researchers said that the analysis of all cognitive tests combined showed that levels of all three lead biomarkers were associated with worse cognitive performance, with the association between bone lead and letter fluency scoring dramatically different from the other bone lead/cognitive score associations.
They said that even though the levels of patella and blood lead were linked with worse cognitive function, their findings were statistically significant only for tibia lead, which typically reflects longer-ago exposures than patella lead.
Based on their observations, the researchers came to the conclusion that lead exposures in the distant past might be more important than relatively recent exposures in influencing cognitive function in older women.
“The identification of modifiable risk factors for cognitive decline may provide important clues for delaying or even preventing dementia,” wrote first author Jennifer Weuve and colleagues.
The study has been published in the journal Environmental Health Perspectives (EHP).
The journal’s editor-in-chief, Dr. Hugh A. Tilson, said: “Findings in this study are important because of their long-range consequences on the public health of an aging generation. Impaired cognition and cognitive decline in older women are associated with heightened risks of dementia, physical disability, hospitalisation and reduced quality of life in later years.” (ANI)
- Does air pollution erode mental sharpness? - Feb 14, 2012
- Swimming in indoor pools could increase cancer risk - Sep 13, 2010
- Chemicals in mother's blood linked to child's obesity - Oct 10, 2010
- Men with high levels of bone lead 6 times more likely to die from heart disease - Sep 10, 2009
- Lead in bone heightens cardiovascular death risk - Sep 10, 2009
- Long-term exposure to pesticides linked to dementia - Dec 02, 2010
- Migraines do not hurt your brain - Aug 12, 2012
- Light-to-moderate alcohol consumption helps stave off dementia - Mar 02, 2011
- Spouses of dementia sufferers 'six times more likely to develop same condition' - May 05, 2010
- Fat levels in blood may lead to Alzheimer's - Jul 19, 2012
- High risk factors for stroke linked to some cognitive decline - Apr 13, 2011
- Alzheimer's hits women more severely than men - Aug 26, 2012
- Study reveals that Sleep apnea is linked to dementia - Aug 10, 2011
- Elderly? Get some sunshine to prevent falls - May 05, 2011
- Prenatal air pollution exposure 'adversely affects kids' cognitive development' - Apr 21, 2010
Tags: biomarkers, cognition, cognitive decline, cognitive function, cognitive performance, cognitive tests, community settings, cumulative exposure, dementia, environmental health perspectives, environmental health sciences, fluency, institute of environmental health, modifiable risk factors, national institute of environmental health sciences, older women, patella, public health, tibia, tilson