Controlling blood vessels could help combat obesityJanuary 8th, 2009 - 1:26 pm ICT by ANI
Washington, Jan 8 (ANI): Scientists have found that controlling blood vessel development may help fight obesity and diabetes.
As the growth of fat cells and their metabolism depend on oxygen and blood-borne nutrients, one possible way to regulate the amount of body fat for fighting obesity, can therefore be to affect the development of blood vessels in the adipose tissue.
In their study, researchers at Karolinska Institutet exposed mice to low temperatures and found that the animals developed more blood vessels in their adipose tissue and were able to metabolise body fat more quickly.
They also showed that the adipose tissue transformed from ”white” fat to ”brown” fat, which has higher metabolic activity and which breaks down more quickly.
“This is the first time it’’s been shown that blood vessel growth affects the metabolic activity of adipose tissue rather than vice versa. If we can learn how to regulate the development of blood vessels in humans, we”d open up new therapeutic avenues for obesity and metabolic diseases like diabetes,” said Professor Yihai Cao, who led the study.
Brown fat releases heat when it breaks down, and is mainly found in hibernating animals.
In humans, it is found in newborn babies, but scientists believe that by controlling blood vessel development it might be possible to transform white fat to brown fat in adults as well. (ANI)
- Fat outside of the arteries linked to cardiovascular disease - Nov 17, 2010
- Drug helps monkeys shed weight, holds hope for humans - Nov 13, 2011
- Does 'starving' fat suppress appetite and reverse obesity? - Feb 02, 2010
- Potential new target for diabetes, heart disease treatments identified - Nov 17, 2010
- Exceeding 'cell fat storage capacity' might trigger type-2 diabetes - Nov 09, 2010
- 'Dual switch' that regulates fat formation may harbour obesity cure - Apr 09, 2011
- Burning brown fat could be the key to tackling obesity - Dec 21, 2010
- Protein that modulates metabolic dysfunction in obesity identified - Jun 18, 2010
- Why a class of diabetes drugs boosts weight gain - May 02, 2011
- Lower levels of 'rotten eggs' gas in blood linked to obesity, diabetes - Apr 28, 2010
- Human enzyme holds promise of weight loss - Nov 15, 2011
- Successful dieting may be all in the mind - Jul 07, 2010
- Apple compound may help burn fat, reduce obesity - Jun 21, 2012
- Potential new non-insulin treatment for type 1 diabetes found - Mar 25, 2011
- Cannabis can help treat obesity - Jul 08, 2012
Tags: adipose tissue, avenues, blood vessel development, blood vessel growth, blood vessels, brown fat, cao, combat obesity, fat cells, fight obesity, fighting obesity, hibernating animals, metabolic activity, metabolic diseases, metabolism, mice, newborn babies, nutrients, oxygen, study researchers