Cognitive impairment linked to increased death risk regardless of race
June 9th, 2009 - 1:15 pm ICT by ANI ( Leave a comment )Washington, June 9 (ANI): A new study has shown that Alzheimer’s disease and its precursor, mild cognitive impairment, is linked to an increased risk of death among both white and African American older adults.
“Data from two national surveys suggest that life expectancy among patients with Alzheimer’s disease may be greater for African Americans than for whites,” the authors said.
“However, not all surveys have reported this difference. Furthermore, in these surveys, the diagnosis of Alzheimer’s disease is not based on a uniform clinical evaluation but derived from medical records, increasing the likelihood of substantial variation in the quality of diagnostic classifications,” they added.
For the study, Robert S. Wilson, Ph.D., and colleagues at Rush University Medical Center, Chicago, examined 1,715 older adults (average age 80.1, 52.5 percent African American) from four adjacent neighbourhoods in Chicago.
Each participant had a clinical evaluation that included medical history, a neurological examination and cognitive function testing. Based on these evaluations, an experienced physician diagnosed 296 of the participants with Alzheimer’s disease, 597 with mild cognitive impairment and 20 with other forms of dementia, while 802 had no cognitive impairment.
During up to 10 years of follow-up, 634 individuals died including 25.8 percent of those without cognitive impairment, 40.4 percent of those with mild cognitive impairment, 59.1 percent of those with Alzheimer’s disease and 60 percent of those with other forms of dementia.
“Compared with people without cognitive impairment, risk of death was increased by about 50 percent among those with mild cognitive impairment and was nearly three-fold greater among those with Alzheimer’s disease. These effects were seen among African Americans and whites and did not differ by race,” the authors said.
The study is published in the June issue of Archives of Neurology, one of the JAMA/Archives journals. (ANI)
- Cognitive decline 4 times faster in Alzheimer's patients - Mar 23, 2010
- Hearing loss linked to development of dementia - Feb 15, 2011
- People with thin brain structure 'at greater risk for Alzheimer's' - Apr 14, 2011
- Reduced muscle strength linked to Alzheimer's risk - Nov 10, 2009
- Brain exercises may be good initially, but speed up dementia later - Sep 02, 2010
- High levels of 'good' cholesterol linked to lower risk of Alzheimer's - Dec 14, 2010
- High BP may help predict dementia in older adults - Feb 09, 2010
- It's official: Men have more memory problems than women - Sep 07, 2010
- Depression is a risk factor, not an early sign of Alzheimer's - Jul 06, 2010
- Now, 3 biomarkers in spinal fluid could classify patients with Alzheimer's - Aug 10, 2010
- DHA may improve memory and learning in older adults: Study - Nov 09, 2010
- Difficulties in performing daily activities linked to dementia - Sep 15, 2009
- 'Sweet 16' tool could rapidly identify cognitive impairments - Nov 09, 2010
- Clogged arteries can also cause clouded thinking - Jul 22, 2011
- Large doses of B-complex vitamins may help slow progression of dementia - Oct 26, 2010
Tags: african americans, archives of neurology, clinical evaluation, cognitive function, death risk, dementia, diagnostic classifications, life expectancy, medical history, medical records, mild cognitive impairment, neighbourhoods, neurological examination, older adults, precursor, rush university medical center chicago, s wilson, substantial variation, two national surveys, university medical center