Breast cancer survivors ‘more likely to fall’March 5th, 2011 - 2:27 pm ICT by ANI
Washington, Mar 5 (ANI): A new research has revealed that combined effects of chemotherapy and endocrine therapy may increase the risk of bone fractures in breast cancer survivors.
Researchers from the Oregon Health and Science University Knight Cancer Institute, Portland, asked post-menopausal breast cancer survivors whether they had fallen in the past year and then tracked their falls over a six-month study period.
They found evidence that women who have survived breast cancer may fall more often than their peers.
“Our study is the first to consider how breast cancer treatment may increase fall risk by using a comprehensive set of objective measures of fall risk and by exploring mediators of the treatment-falls relationship,” commented Kerri M. Winters-Stone, PhD, Associate Professor and Associate Scientist, Oregon Health & Science University, School of Nursing and a member of the Knight Cancer Institute. “Our findings suggest that recently treated postmenopausal breast cancer survivors have higher rates of falling compared with population averages for community-dwelling older adults. Balance disturbances may explain how treatment could have contributed to falls in breast cancer survivors.”
Investigators found that 58 percent of breast cancer survivors had experienced a fall in the previous year and almost half (47 percent) fell within 6 months after joining the study, a rate nearly double the 25 percent to 30 percent annual fall rate reported for community-dwelling older adults over 65 years of age.
Researchers measured a comprehensive set of neuromuscular and balance characteristics known to be associated with falls in 59 study participants. They found that only balance discriminated breast cancer survivors who fell from those who did not. The study findings also suggest that the balance problems may have been related to changes in the vestibular system that were associated with chemotherapy treatment.
Professor Winters-Stone stated, “Falls in breast cancer survivors are understudied and deserve more attention, particularly in light of the increase in fractures after breast cancer treatment and the relationship of falls to fractures. Our findings add to growing evidence that fall risk is increased in breast cancer survivors and that vestibular function may underpin associations between breast cancer treatment and falls.”
The study is scheduled for publication in the April issue of the Archives of Physical Medicine and Rehabilitation. (ANI)
- Breast cancer survivors are at higher risk for hip fractures - Feb 03, 2011
- This drug can reduce breast cancer recurrence - Sep 27, 2011
- Fracture prone? Blame your genes - Apr 22, 2012
- Obesity in postmenopausal women increases risk for fractures - Mar 26, 2011
- Breast cancer patients with diabetes '50pc more likely to die' - Jan 19, 2011
- Exercising to piano music 'helps reduce falls among elderly' - Nov 23, 2010
- Breast cancer survivors with physical limitations more likely to die - Sep 25, 2010
- Elderly can blame low sodium for fractures and falls - Nov 21, 2010
- Soy food safe for breast cancer survivors - Apr 06, 2011
- Exercise best medicine for chronic disease - Nov 11, 2011
- Pregnancy-related cancers up by 70 percent - Sep 11, 2012
- Body fat distribution linked to a higher risk of ER-negative breast cancer - Dec 16, 2010
- Decrease in hormone therapy use may reduce breast cancer risk - Nov 09, 2009
- Gene mutation ups blood-clot risk in women taking breast cancer treatment - Jun 17, 2010
- Breast cancer cases in India to double by 2015: Experts - Oct 19, 2011
Tags: associate scientist, balance problems, bone fractures, breast cancer, breast cancer survivors, breast cancer treatment, cancer institute, chemotherapy, effects of chemotherapy, mediators, objective measures, older adults, oregon health, population averages, school of nursing, science university, study findings, study participants, study period, vestibular system