Brain protein that helps us learn and remember things identified
November 22nd, 2007 - 12:30 pm ICT by admin - Send to a friend:Washington, November 22 (ANI): A study of rats brains at Northwestern University’s Feinberg School of Medicine has revealed the protein that helps people learn and remember what they have learnt.
The protein that allows the brain do this is called kalirin-7, say the researchers.
Given that people with Alzheimer’s disease and schizophrenia have reduced levels of Kalirin in their brains, the researchers believe that the discovery of kalirin’s role in learning offers new insight into the pathophysiology of these disorders.
“Identifying the key role of this protein in learning and memory makes it a new target for future drug therapy to treat or delay the progression of these diseases,” said Peter Penzes, lead author of the study and assistant professor of physiology at the Feinberg School.
Writing about their findings in the journal Neuron, the researchers have revealed that kalirin behaves like a personal trainer for the human memory.
According to their report, when people learn something new, kalirin bulks up the synaptic spines in their brain, which resemble tiny, white mushrooms. The spines grow bigger and stronger as the lesson is repeated.
The researchers say that it works the same whether a person is learning a new cell phone number, skiing a new double black diamond slope, or testing a pumpkin cheesecake recipe.
Synaptic spines are the sites in the brain where brain cells talk to each other.
“If these sites are bigger, the communication is better. A synapse is like a volume dial between two cells. If you turn up the volume, communication is better. Kalirin makes the synaptic spines grow,” Penzes said.
The researcher says that kalirin’s role in learning and memory helps explain why continued intellectual activity and learning delay cognitive decline in old age.
“It’s important to keep learning so your synapses stay healthy,” Penzes said. (ANI)
Related Stories
- Master regulatory molecule for brain wiring identified - November 22, 2007
- Short-term stress can make us forgetful - March 12, 2008
- Short-term stress can impair memory and learning - March 12, 2008
- Researchers identify mechanisms of memory - April 24, 2008
- Stopping a receptor called ‘nogo’ opens ways to keep the brain sharp - March 19, 2008
- Scientists selectively and safely erase memories in mice - October 23, 2008
- Scientists identify mechanism that helps fruit flies lock-in memories - March 30, 2008
- Marine snails to shed light on human long-term memory - June 20, 2008
- Scientists zero in on origins of main ingredient of Alzheimer’s plaques - April 10, 2008
- Continuous brain cell generation key to learning and memory - September 1, 2008
- Digestion of harmful protein linked to Alzheimers - July 28, 2008
- Missing brain protein may be one of the culprits behind autism - December 6, 2007
- Study on octopus sheds new light on how the brain stores, recalls memory - June 18, 2008
- Mental, physical activity delays dementia in Huntington’s disease - January 25, 2008
- Study cast new light on how memory is stored - April 24, 2008
- brain protein
- brains
- cells
- cognitive decline
- feinberg school of medicine
- human memory
- intellectual activity
- learn something new
- learning and memory
- northwestern university
- pumpkin cheesecake recipe
- schizophrenia
- spines
- stay healthy
- synaptic
- target
- turn up the volume
- volume dial
Posted in Health Science, |

