BPA exposure may lead fertility problems in female offspring
December 2nd, 2010 - 5:25 pm ICT by ANIWashington, Dec 2 (ANI): A new study has found that exposure to a ubiquitous environmental chemical during pregnancy may impair reproductive capacity of female offspring.
Fertility decreased over time in female mice that had been exposed during fetal and neonatal (perinatal) development to doses of bisphenol-A (BPA) that were lower than or equal to human environmental exposure levels.
“Mice exposed to BPA in the womb and during nursing subsequently had fewer successful pregnancies and delivered fewer pups over the course of the study,” reported one of the study’s co-senior authors, Ana M. Soto, professor of anatomy and cellular biology at Tufts University School of Medicine (TUSM) and member of the cell, molecular and developmental biology program faculty at the Sackler School of Graduate Biomedical Sciences.
At the highest of three doses tested, only 60pc of the BPA-exposed mice had four or more deliveries over a 32-week period, compared with 95pc in the unexposed control group.
Decline of the reproductive capacity of the female mice in this study was not obvious at first pregnancy, when the animals were very young, but manifested later in life with a decline in number of pups born per delivery.
The study has been published online in advance of print on December 2 in Environmental Health Perspectives. (ANI)
- High plastic chemical levels in urine ruins males' sex drive - May 28, 2010
- Early-life exposure to BPA may harm testis function in adulthood - Jun 22, 2010
- Mum's exposure to some plastic may increase kid's asthma risk - Feb 04, 2010
- Exposure to chemical fosters anxiety - Sep 09, 2012
- Increasing urine BPA level tied to worsening male sexual function - May 28, 2010
- Packaging chemical could cheat men of sex appeal - Jun 29, 2011
- Exposure to low doses of BPA alters mice ovaries - Aug 26, 2010
- Mum's exposure to BPA may increase child asthma risk - Feb 04, 2010
- Workplace BPA exposure ups male sexual dysfunction risk - Nov 11, 2009
- Plastic bottle compound harms several generation - Jun 17, 2012
- Cash receipts, currency notes carry toxic hazards: Study - Jul 12, 2012
- BPA exposure may lead to fertility problems in female offspring - Feb 26, 2010
- Exposure to plastics chemical linked to reduced semen quality - Oct 28, 2010
- Chemicals in plastic may pose cancer risk - May 26, 2010
- Human exposure to plastics chemical much higher than previously thought - Sep 21, 2010
Tags: anatomy, cellular biology, control group, deliveries, developmental biology program, environmental chemical, environmental exposure, environmental health perspectives, exposure levels, female mice, female offspring, fertility problems, graduate biomedical sciences, pregnancies, program faculty, sackler school, school of medicine, tufts university school, tufts university school of medicine, womb