Bodys natural painkiller identified

December 19th, 2007 - 5:28 pm ICT by admin  

London, Dec 19 (ANI): A new study in mice has shown that getting rid of an enzyme called c-Kit increases pain tolerance.

Gary Lewin and colleagues at the Max Delbruck Centre for Molecular Medicine in Berlin, Germany, said that the new finding could lead to the development of a new class of painkillers that work by blocking the enzyme.

The skin holds more than a million nociceptors, or bare nerve endings, around half of which fire in response to pain, reports New Scientist.

During the study, researchers found that mice which cannot make c-Kit took 40 per cent longer to jerk their paw away from a hot infrared beam.

Also, the beam had to be 6 degrees Celsius hotter to make the nociceptors fire.

On the contrary, in normal mice, c-Kit seems to be what makes inflamed skin feels pain more easily. (ANI)

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