Thaindian News

London, April 9 (ANI): If you can’t get through the day without a caffeine hit, your genes may be to be blame.

U.S. researchers have revealed that some people inherit genes, which make them more reliant on caffeine, reports the Daily Mail.

Those with the ‘caffeine addict’ genes need to drink more coffee or tea to get the same buzz.

The researchers came to the conclusion after scrutinising the DNA and diets of 45,000 people.

This flagged up two genes associated with the high intake of tea, coffee, chocolate and caffeinated soft drinks such as colas.

One - CYP1A2 - is key to the breakdown of caffeine in the liver. The other, called AHR, regulates the first.

“It’s been known for decades that this CYP1A2 gene is what metabolized caffeine,” said researcher Neil Caporaso.

“But using new technology, what we showed for the first time is that it appears responsible for the inherited differences in how people drink coffee.

“The point is that the way we drink caffeine is not just random - it’s related to the genetic hand of cards you were dealt.

“If you break it down more quickly, you require more caffeine to achieve the same “buzz” or to avoid withdrawal after stopping all caffeine,” he said.

Those who are tipped towards higher consumption drink about 40mg of caffeine more a day than others, equal to around a third of a cup of coffee or one can of cola.

The study is published in the journal PLoS Genetics. (ANI)