Being depressed could break your heart, literallyMarch 10th, 2009 - 2:41 pm ICT by ANI
Washington, Mar 10 (ANI): Relatively healthy women with severe depression are at increased risk of cardiac events, including sudden cardiac death (SCD) and fatal coronary heart disease (CHD), says a new study.
In the study, boffins found that much of the relationship between depressive symptoms and cardiac events was mediated by cardiovascular disease risk factors, such as high blood pressure, high cholesterol and smoking.
“It’’s important for women with depression to be aware of the possible association between depression and heart disease, and work with their health care providers to manage their risk for coronary heart disease,” says William Whang, M.D., M.S., Division of Cardiology, Columbia University Medical Center, and lead investigator of the study.
“A significant part of the heightened risk for cardiac events seems to be explained by the fact that coronary heart disease risk factors such as high blood pressure, diabetes, elevated cholesterol, and smoking were more common among women with more severe depressive symptoms, the expert added.
To reach eth conclusion, Dr. Whang and his colleagues prospectively studied 63,469 women from the Nurses Health Study who had no evidence of prior heart disease or stroke during follow-up between 1992 and 2004.
Self-reported symptoms of depression and use of antidepressant medication were used as measures of depression. To best identify those with clinical depression, researchers specifically examined women with the most severe symptoms defined by a validated 5-point mental health index score of less than 53 or regular antidepressant use.
The study found that women with more severe depressive symptoms or those who reported taking antidepressants were at higher risk for SCD and fatal CHD. In particular, women with clinical depression were more than twice as likely to experience sudden cardiac death.
Surprisingly, this risk was associated more strongly with antidepressant use than with depressive symptoms.
“These data indicate the link between depression and serious heart rhythm problems may be more complex than previously thought,” says Sanjiv M. Narayan, M.D., F.A.C.C., University of California, San Diego, who co-authored the accompanying editorial with colleague, Murray Stein, M.D. (ANI)
- Severe depression can trigger heart attacks in women - Mar 10, 2009
- Some 'good' cholesterol unable to protect heart - May 09, 2012
- Working overtime raises heart disease risk - May 12, 2010
- Fasting ensures good health, protects heart - Apr 04, 2011
- Routine periodic fasting good for health, heart - Apr 04, 2011
- Therapy to prevent heart failure more beneficial for women than men - Feb 08, 2011
- Sudden cardiac death tied to slower electrical currents - May 22, 2012
- South Asians more prone to heart attacks than whites - Jun 29, 2010
- Older anti-depressants linked to heart risk - Dec 01, 2010
- Biomarkers for postmenopausal cardiovascular disease found - Jul 28, 2010
- Working overtime is bad for the heart - May 17, 2010
- Depression, heart disease combo more deadly than either one alone - Sep 16, 2010
- Crude oil chemical linked to congenital heart disease - May 01, 2011
- Obesity is a killer in its own right - Feb 15, 2011
- Trans fats 'can prove dangerous for women with heart disease' - Apr 09, 2010
Tags: cardiac events, cardiovascular disease risk, cardiovascular disease risk factors, clinical depression, columbia university medical, coronary heart disease, coronary heart disease risk, coronary heart disease risk factors, disease chd, disease risk factors, health care providers, heart disease risk, heart disease risk factors, index score, mental health index, nurses health, severe depression, sudden cardiac death, symptoms of depression, university medical center