Aspirin, ibuprofen offer no protection against skin cancer
February 16th, 2010 - 2:16 pm ICT by ANIWashington, Feb 16 (ANI): The use of non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen and celecoxib offer no protection against a common skin cancer, according to a new study.
Non-steroidal anti-inflammatory drugs (NSAIDs) reduce pain and inflammation by blocking an enzyme involved in producing inflammatory compounds.
Maryam M. Asgari, of Kaiser Permanente Northern California, Oakland, and colleagues studied 415 health plan members who were diagnosed with squamous cell carcinoma in 2004 and 415 control patients who were the same age, [Bleep] and race but had no history of skin cancer. Participants completed a questionnaire about NSAID use in the 10 years prior.
The majority of participants (61 percent) reported regular use of NSAIDs within the previous ten years, including 48 percent who used aspirin, 18 percent who used ibuprofen, 5 percent who used naproxen and 4 percent who used nabumetone.
“Regular use of any NSAID was not associated with a reduction in squamous cell carcinoma risk. Although NSAID users whose exposure was of short duration (one to three years) appeared to be at somewhat increased risk for squamous cell carcinoma, we found no consistent effects of duration of use of any NSAID on squamous cell carcinoma risk,” the authors said.
Squamous cell carcinoma risk also did not appear to change regardless of NSAID dose, whether the medications were administered by a pharmacy nor with any individual type of NSAID medication.
The study will appear in the April print issue of Archives of Dermatology, one of the JAMA/Archives journals. (ANI)
- Widely used arthritis pill shows promise against skin cancer - Dec 03, 2010
- Painkillers double risk of miscarriage: Study - Sep 07, 2011
- Common painkillers increase risk of heart problems: Study - Jan 12, 2011
- Painkillers shoot up death risk in heart attacks - May 10, 2011
- New aspirin curbs 11 kinds of cancer, shrinks tumours - Mar 09, 2012
- Ibuprofen may reduce risk of Parkinson's disease - Mar 03, 2011
- Taking ibuprofen regularly cuts Parkinson's disease risk - Feb 18, 2010
- Tumeric derivative found promising in tendinitis - Aug 11, 2011
- Oral and topical agents prevents UV-induced skin cancer - Aug 06, 2010
- Ibuprofen more effective than paracetamol for period pain - Jan 20, 2010
- Painkillers : nonsteroidal anti-inflammatory drug - Jun 25, 2008
- Study examines aspirin's ability to protect against colorectal cancer - Mar 10, 2011
- Topical treatments offer effective local pain relief - Jun 16, 2010
- Ibuprofen painkillers cut risk of dying among elderly - Jul 08, 2010
- NSAID use linked to increased risk of erectile dysfunction - Mar 03, 2011
Tags: anti inflammatory drugs, aspirin, bleep, carcinoma, compounds, control patients, dermatology, health plan members, history of skin cancer, inflammation, jama, kaiser permanente, nabumetone, naproxen, non steroidal anti inflammatory drugs, northern california, nsaid users, nsaids, skin cancer, squamous cell carcinoma